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Powerful explosion at Massachusetts pharmaceutical plant sends 4 to hospital, 1 worker left unaccounted for

A powerful explosion at a pharmaceutical plant in Massachusetts that has a checkered history left one worker missing, sent four people to the hospital and blew an industrial-sized vat into a parking lot, officials said Thursday.

The explosion happened around 1 a.m. at the Sequens/PCI Synthesis plant in Newburyport, officials said. Video footage showed most of the roof torn off a building, and the blast blew a vat from inside the building 30 feet into a parking lot, acting Fire Chief Stephen Bradbury III said in a news release.

It wasn’t immediately known what caused the explosion, and it wasn’t clear what role, if any, the vat played in the explosion.

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“There is major structural damage to the building, preventing firefighters and technical rescue crews from entering the building to begin a search,” Bradbury said.

Massachusetts factory explosion

A vat that was once inside a Newburyport, Massachusetts, pharmaceutical plant was hurled into the parking lot by an explosion, on May 4, 2023.  (Keith Sullivan/The Newburyport Daily News via AP)

There is no danger to nearby homes, he said, but workers at the industrial park where the plant is located were asked to avoid the area.

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The four workers were sent to the hospital as a precaution, were not injured and were released. But one worker was not yet accounted for.

“All our attention is focused on the situation of our employees,” a company statement said.

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In 2020, authorities said a chemical reaction caused a series of explosions at the plant. That happened a year after the Occupational Safety and Health Administration found “serious” violations in the company’s management of highly hazardous chemicals, according to online agency records.

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